Leamington's looking to close out its first round playoff series in St. Mary's, while the LaSalle Vipers can gain control of their series, hosting Sarnia.
The Flyers already lead their best-of-seven 3-0 after a 10-2 thrashing of the Lincolns on Sunday.
The series between the one and eight seeds hasn't been close, as Leamington's outscored St. Mary's 22-4 so far.
LaSalle and Sarnia, on the other hand, continue to exchange blows, leading to a 2-2 series after four games.
The Vipers have come away with two home wins, outscoring the Legionnaires 12-3 in those contests.
Puck drop at the Vollmer Complex is set for 7pm.
