Lambton OPP say they seized about $5,700 worth of drugs in a traffic stop on the night of Friday, June 14 in Thedford.
At around 11 p.m., an officer pulled over a vehicle on Main Street for a Highway Traffic Act violation.
Police said a quantity of suspected illegal drugs was found within the vehicle.
Officers seized 43 grams of suspected fentanyl, 29 grams of suspected cocaine, and a quantity of pills.
A 47-year-old from Kettle and Stony Point First Nation is charged with two counts of possession of a schedule one substance for the purpose of trafficking.
They were released and will appear before the Ontario Court of Justice in Sarnia on August 7.
A 47-year-old from Thedford is charged with possession of a schedule one substance - Opioid. They remain in custody due to outstanding arrest warrants.
